Ubuntu has a PHP package and a MySQL package for 64 bit, so yes. Drupal, being written in an interpreted language is more or less platform/processor independent. The real question is whether you can get PHP and MySQL to run. In this case, you can.
In this link is very useful to you,http://www.howtoforge.com/ubuntu_lamp_for_newbiesOn Fri, Feb 11, 2011 at 12:43 PM, Kamal Palei <kamal.palei.1975@gmail.com> wrote:
Hi AllI wanted to install Drupal 6 / Drupal 7 in a 64 bit Ubuntu machine.Just wanted to check if Drupal is compatible with 64 bit Ubuntu Linux machine.My machine's hardware profiles are ----------------------------------------------------1. CPU intel core i5 650 boxed 3.2 ghz socket 1156
2. MB intel P55 Chipset DH55P J Boxed
3. HDD WD SATA 2Tb 64MB cache
With above hardware profile, and Ubuntu 10.04 (64 bit) linux environment, I am planning to install Drupal6/7.If somebody has already done it , please share if you faced any problems.Also in a 64 bit ubuntu linux machine, which webserver is recommonded.I found some people using XAMPP. Is it the best one or you have someother recommondations.Load on web server will be high, at high load, I am looking for high performing webserver.Best RegardsKamal