[support] Panels or block ?

Hi all. I'm rebuilding site and I have a "performance problem" with a page.

This page needs to contain text (node body) and a block from a view. Now, I can link the block in the "content" region and via block's settings I can say Drupal to display this block only when the users are viewing that page. But I could have the need to have some other pages of this type (with other blocks). My question: is this (block-region) the best solution or is better to use "panel" module ? And: is the panel modules load for every page or only when it's required ?

Statistic of this site say me that the page views are 1.5M+, 50% are from forum and other 50% are internal page. This particolar page generate 10K+ page views.

Tnx for all.

M.